Development of neuronal shape, connectivity and electrical activity of neural networks







A developing neural network is a dynamic, self-modifying system. A feedback loop exists between the development of neuronal shape, type and distribution of ionic channels, and connectivity on one hand, and electrical neuronal and network activity on the other hand.

In this context the following problems have been studied:

Web resources

General / Courses / Textbooks

The BrainArt Gallery - Evian Gordon

Comparative Mammalian Brain Collections

Neurogenetik - online
Kapitel 34,  Lehrbuch der Genetik, von Seyffert, Wilhelm. Gustav Fischer Verlag 1998.

Development of the mammalian central nervous system
(Pasko Rakic, Section of Neurobiology at Yale University School of Medicine, New Haven CT

Introduction to Neurobiology Fall 2000

Developmental Biology - online, by Scott F. Gilbert, Sinauer Associates, 2000.

Foundations of Neurobiology - Delcomyn web chapters

Dendrites

Neuronal Morphogenesis
Hilary G.E. Hentschel, Emory University, Department of Physics, Atlanta GA

Theoretical Neurobiology: Modelling the Development of the Nervous System
Jaap van Pelt, Netherlands Institute for Brain Research, Amsterdam, The Netherlands

Synaptic integration and information processing in neuronal dendrites
Michael Häusser, University College London, UK

Pattern formation and neuronal development

Theoretical aspects of pattern formation and neuronal development
Alfred Gierer, Hans Meinhardt, Max-Planck-Institut für Entwicklungsbiologie, Tübingen

Cortical Map Development  / Axon Guidance - Mathematical modeling and in vitro experiments
Geoffrey J. Goodhill, Computational Neuroscience Laboratory, Department of Neuroscience, Georgetown University Medical Center, Washington DC, USA

Evolutionary Artificial Neural Networks
Alistair Rust, European Bioinformatics Institute,  Hinxton, Cambridge, UK

From Neurons to Brain: Adaptive Self-Wiring of Neural Networks
Ronen Segev, Tel Aviv University, Israel

Biological Modeling and Visualization
Przemyslaw Prusinkiewicz, Department of Computer Science, University of Calgary, Calgary, Alberta, Canada

Self-organization and electrophysiological dynamics of mammalian networks in cell culture
Center for Network Neuroscience, University of North Texas, Denton TX

Spatio-temporal activity patterns

Complex spatio-temporal patterns of discharge in the central nervous system

Methods / Software tools

Dendritica - Software tools for studying dendritic signalling

BLISS/SYNOD - Simulation environment for neural systems

Spiking Neural Networks -SPINN SoC

Signal Processing Techniques for Spike Train Analysis using Matlab - Gabbiani  / Koch

Neuronal assemblies: Multi-electrode recording,  spike  train analysis, theoretical and simulation studies
George Gerstein, U. of Pennsylvania, Neuroscience

Neural Ensemble Physiology
Miguel A.L. Nicolelis,  Department of Neurobiology, Duke University

NEOSIM - Neural Open Simulation - Software tools for large scale systems modelling of the
nervous system

SNNAP - Simulator for Neural Networks and Action Potentials

Neuronal Pattern Analysis  Beckman Institute, University of Illinois at Urbana Champaign,  Urbana  IL

New Neuroscience Technologies for Studying Learning in Vitro
Steve M. Potter, Caltech Division of Biology, Pasadena CA

  • multi-electrode array culture dishes
  • 2-photon time-lapse microscopy
  • high-speed imaging of neural activity
  • neurally-controlled computer-simulated animals
  • Multi-Electrode Arrays

    MEA-Tools - MATLAB Tools for the analysis of multi-neuronal data recorded with multi-electrode arrays

    Multi-electrode Recording - Links

    Neuronal Morphology Archive

    Synapse Web - Tools for analysis and reconstruction of three-dimensional objects from serial sections

    Confocal Microscopy_- Related Links

    Innovationslolleg "Komplexe und zelluläre Sensorsysteme"-Universität Rostock

    Publications

    Computational Neuroscience: Realistic Modeling for Experimentalists, edited by E.De Schutter, CRC Press 2000

    Emergent Neural Computational Architectures based on Neuroscience, edited by S. Wermter, J. Austin, D. Willshaw, Springer 2001

    Digital Simulation of Spiking Neural Networks, in: Pulsed Neural Networks, edited by W. Maas and C.M. Bishop, MIT Press 1998 - download